Info
🌱 來自：cancer pharmacology
Antibody Drug Conjugates
| Agent | Epitope | Conjugated Drug |
|---|---|---|
| Ado-trastuzumab emtansine | HER2 | Mertansine |
| Enfortumab vedotin-ejfv | Nectin 4 | Monomethyl auristatin E (MMAE) |
| Fam-trastuzumab deruxtecan-nxki | HER2 | DX-8951 derivative, DXd |
| Moxetumomab pasudotox-tdfk | CD22 | Pseudomonas exotoxin PE38 |
| Polatuzumab vedotin-piiq | CD79b | MMAE |
| Sacituzumab govitecan-hziy | Trop-2 | Irinotecan derivative SN-38 |
| Tagraxofusp-erzs | CD123 | Diphtheria toxin |
List
- Ado-trastuzumab emtansine (Kadcyla) a.k.a TDM1
- Enfortumab vedotin-ejfv (Padcev)
- Fam-trastuzumab deruxtecan-nxki (Enhertu) T-DXD
- Moxetumomab pasudotox-tdfk (Lumoxiti)
- Polatuzumab vedotin-piiq
- Sacituzumab govitecan
- Tagraxofusp-erzs (Elzonris)