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Intra- RBC findings of Peripheral Smear Findings

Basophilic stippling (ribosomes) → abnl Hb, sideroblastic, megaloblastic Heinz bodies (denatured Hb) → G6PD deficiency, thalassemia Howell-Jolly bodies (nuclear fragments) → splenectomy or functional asplenia (eg, advanced sickle cell) Nucleated RBCs → hemolysis, extramedullary hematopoiesis