Info
treatment of waldenstrom’s macroglobulinemia (WM)
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Hyperviscosity:
- plasmapheresis;
- limit transfusions if possible (worsen hyperviscosity)
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Sx (eg, prog. anemia):
- ritux ± chemo (eg, bendamustine, Cy, etc.);
- ritux + ibrutinib (NEJM 2018;378:2399);
- zanubrutinib (Lancet Haem 2020;7:e837);
- everolimus or HSCT in salvage