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How should response be measured in patients receiving neoadjuvant chemotherapy
Recommendations Recommendation 2.1. Patients receiving neoadjuvant therapy should be monitored for response with clinical examination at regular intervals. Breast imaging may be used to confirm clinical suspicion of progression and for surgical planning. When imaging is used, the modality that was most informative at baseline-mammography, ultrasound, or magnetic resonance imaging-should be used at follow-up (Type: informal consensus; Evidence quality: insufficient; Strength of recommendation: moderate). Recommendation 2.2. Blood- and tissue-based biomarkers should not be used for monitoring patients receiving neoadjuvant therapy (Type: informal consensus; Evidence quality: insufficient; Strength of recommendation: strong). Recommendation 2.3. Pathologic complete response (pCR), defined as absence of invasive disease in breast and lymph nodes, should be used to measure response to guide clinical decision making (Type: informal consensus; Evidence quality: insufficient; Strength of recommendation: moderate).
Siblings
- Which patients with breast cancer are appropriate candidates for neoadjuvant systemic therapy
- How should response be measured in patients receiving neoadjuvant chemotherapy
- What neoadjuvant systemic therapy regimens are recommended for patients with TNBC
- What neoadjuvant treatment is recommended for patients with HR-positive HER2-negative breast cancer
- What neoadjuvant treatment is recommended for patients with HER2-positive disease