Info

tbi

Total body irradiation

  • Doses of total body irradiation used in bone marrow transplantation typically range from 10 to >12 Gy.
  • For reference, an unfractionated (i.e. single exposure) dose of
    • 4.5 Gy is fatal in 50% of exposed individuals without aggressive medical care.
  • The 10-12 Gy is typically delivered across multiple fractions to minimise toxicities to the patient