Info

IDH1_IDH2 mutation

  • 20% of AML
  • isocitrate dehydrogenase (IDH) genes,
  • IDH1 or IDH2.

adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.

  • ivosidenib
  • enasedinib

Treatment algorithm for acute myelogenous leukemia with mutated IDH1 or IDH2