Fever in a traveler from a malaria zone is malaria until proven otherwise; consider a medical emergency → hospitalization & empiric Rx. One ⊖ smear does not r/o.
Other tests based on s/s, labs, exposure, incubation period, geography, and seasonality. O&P exam, CXR, blood smears for filaria/Babesiosis/Borrelia, serologies, STI & HIV, PPD or IGRA, bone marrow aspirate, bx of lymph nodes or skin lesions, CSF studies.