Info
clinical manifestations of overview of lymphoma and CLL
Lymphadenopathy (usually nontender)
HL 🦉
- superficial
- usually cervical/supraclavicular
- ± mediastinal LAN
- nodal disease
- orderly
- anatomic spread to adjacent nodes
NHL 🍋
- diffuse
- nodal and/or extranodal disease with noncontiguous spread
- symptoms reflect involved sites (abdominal fullness, bone pain)
Constitutional (“B”) symptoms:
- fever (>38°)
- drenching sweats
- ↓ weight (>10% in 6 mo)
HL:
- periodic
- recurrent “Pel-Ebstein” fever
- 10–15% have pruritus
- ~35% “B” symptoms
NHL:
- “B” symptoms vary between subtypes
- ~15–50%