Clinical manifestations of Eosinophilic gran with polyangiitis
(Rheumatol 2020;59:iii84)
Initial sx:
- asthma
- sinusitis
- allergic rhinitis (new asthma in adult raises suspicion)
Eosinophilic infiltrative disease:
- transient pulm infiltrates,
- gastroenteritis
- esophagitis
Systemic small-vessel vasculitis:
- neuropathy (mononeuritis multiplex),
- renal (glomerulonephritis),
- skin (palpable purpura, petechial, nodules)
Cardiac:
- coronary arteritis,
- myocarditis,
- CHF
- valvular insufficiency (Medicine 2009;88:236)