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🌱 來自: Important Antibacterial Drug Interactions

Fluoroquinolones of Important Antibacterial Drug Interactions

• Theophyllinea
  • Can result in theophylline toxicity
• Sucralfate; antacids containing aluminum, calcium, or magnesium; ferrous sulfate- and zinc-containing multivitamins
  • Can result in decreased oral absorption of fluoroquinolones. Administer fluoroquinolone 2 h before or 6 h after interacting drug.
• Tizanidinea
  • Can result in increased levels of tizanidine and hypotensive, sedative effects. Monitor for side effects if drugs are given concomitantly. -QTc-prolonging agents (e.g., azoles, sotalol, amiodarone, dofetilide, fluoxetine)
  • Increased risk of cardiotoxicity and arrhythmias. Monitor QTc.