Malignancy workup-adrenal incidentalomas

  • CT and MRI characteristics may suggest adenoma vs. carcinoma
  • Benign features:
    • unenhanced CT <10 Hounsfield units or CT contrast-medium washout >50% at 10 min
    • size <4 cm
    • smooth margins, homogenous and hypodense appearance
    • can follow such incidentalomas w/ periodic scans
  • Suspicious features:
    • size ≥4 cm or ↑ size on repeat scan;
    • >10 Hounsfield units on CT, irregular margins, heterogeneous, dense or vascular appearance;
    • h/o malignancy or young age.
    • Such incidentalomas warrant resection or repeat scan at short interval.
  • Rule out metastatic cancer (and infection) in Pts w/ h/o cancer; ~50% of adrenal incidentalomas are malignant

from adrenal incidentalomas 󰒖