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🌱 來自: cell cycle

Cell cycle specificity of drugs used in the treatment of cancer

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G, to S PHASE

• CDK4/6 INHIBITOR
• palbociclib, abemaciclib, ribociclib

S PHASE- SPECIFIC DRUGS

• cytosine arabinoside,
• hydroxyurea, irinotecan,
• topotecan

S PHASE-SPECIFIC SELF-LIMTING

• 6-mercaptopurine,
• methotrexate

M PHASE-SPECIFIC DRUGS

• vincristine, vinblastine, paclitaxel

CELL CYCLE-NONSPECIFIC DRUGS

• aalkylating agents, nitrosoureas,
• antitumor antibiotics, procarbazine,
• cisplatin, dacarbazine