Info
Clinical manifestations of disseminated gonococcal infection
- Preceded by mucosal infection (eg, cervix, urethra, anus, or pharynx) that is → often asx
- Two distinct syndromes, although Pts can have both:
- Joint-localized: purulent arthritis (40%), usually 1-2 joints (knees >wrists >ankles)
- Arthritis-dermatitis syndrome: triad of polyarthralgias, tenosynovitis, skin lesions 1. polyarthralgias: migratory joint pain, can affect small or large joints 2. tenosynovitis: pain/inflammation of tendon and its sheath in wrists, fingers, ankles, toes 3. skin lesions: gunmetal gray pustules with erythematous base on extremities & trunk
- Rare complications:
- Fitz-Hugh-Curtis syndrome (perihepatitis),
- pericarditis
- meningitis
- myocarditis
- osteomyelitis from direct extension of joint-localized infection