Patterns of LFTs
LFTs異常的四大類DDx
- hepatocellular
- 上升的ALT, aspartate aminotransferase,其他的不一定
- Cholestatic
- Infiltrative
- Nonhepatic
hepatocellular 想四個DDx
- Viral hepatitis, non-alcoholic fatty liver disease
- 一般來說會是ALT>AST
- Alchololic hepatitis
- AST>2*ALT
- Ischemic injury
- 四項都高,因此shock liver的診斷還是把四項都抽一抽
- Wilson Disease
- Aφ : Tbili < 4 (if fulminat)
Cholestatic
Infiltrative
- 反而是Aφ, Bilirubin高
Nonhepatic
- Skeletal muscle injury
- Bone Disease
- Hemolysis