Info
🌱 來自: Huppert’s Notes
Hormone Therapy🚧 施工中
Hormone Therapy
• Definition: Medications that suppress endogenous hormones that drive growth of certain tumor types (e.g., breast, prostate cancer)
• Examples:
- Selective estrogen receptor modulators (SERMs): Tamoxifen used to treat hormone-receptor positive breast cancer
- Aromatase inhibitors (AIs): Anastrozole, letrozole, exemestane. Used to treat hormone-receptor positive breast cancer
- GnRH agonists: Leuprolide. Used for testosterone suppression in prostate cancer and ovarian suppression in breast cancer
- GnRH antagonists: Degarelix
- Selective androgen receptor antagonists: Flutamide, bicalutamide, enzalutamide, apalutamide
- CYP17 inhibitors: Abiraterone blocks synthesis of androgens