respiratory-alkalosis

Etiologies (NEJM 2002;347:43; Crit Care 2010;14:220)

• Hypoxia → hyperventilation: pneumonia, CHF, PE, restrictive lung disease, anemia
• Primary hyperventilation CNS stimulation, pain, anxiety, trauma, stroke, CNS infection, pontine tumors drugs: salicylates toxicity (early), β-agonists, progesterone, methylxanthines, nicotine pregnancy, sepsis, hepatic failure, hyperthyroidism, fever
• Pseudorespiratory alkalosis: ↓ perfusion w/ preserved ventilation (eg, CPR, severe HoTN) → ↓ delivery of CO2 to lungs for excretion; low PaCO2 but ↑ tissue CO2

Explain by ChatGPT

• Hypoxia : (Hypoxia → hyperventilation: pneumonia, CHF, PE, restrictive lung disease, anemia);
• Primary hyperventilation : (CNS stimulation, pain, anxiety, trauma, stroke, CNS infection, pontine tumors drugs: salicylates toxicity (early), β-agonists, progesterone, methylxanthines, nicotine pregnancy, sepsis, hepatic failure, hyperthyroidism, fever);
• Pseudorespiratory alkalosis : (↓ perfusion w/ preserved ventilation (eg, CPR, severe HoTN) → ↓ delivery of CO2 to lungs for excretion; low PaCO2 but ↑ tissue CO2).

窩的英文不太好，只好請估🐶

• 缺氧：（缺氧→換氣過度：肺炎、CHF、PE、限制性肺病、貧血）；
• 原發性過度通氣：（中樞神經系統刺激、疼痛、焦慮、創傷、中風、中樞神經系統感染、腦橋腫瘤 藥物：水楊酸鹽毒性（早期）、β-激動劑、黃體酮、甲基黃嘌呤、尼古丁 妊娠、敗血症、肝功能衰竭、甲狀腺功能亢進、發燒）；
• 假性呼吸性鹼中毒：（↓ 保持通氣的灌注（例如，CPR，嚴重的 HoTN）→ ↓ 將 CO2 輸送到肺部進行排泄；低 PaCO2 但 ↑ 組織 CO2）。