Info

Hestia Criteria for Outpatient Pulmonary Embolism Treatment

Hemodynamically unstable

sBP <100 mmHg and HR >100, needing ICU care, or by clinician judgment

Thrombolysis or embolectomy needed

For reasons other than hemodynamic instability

Active bleeding or high risk for bleeding

GI bleeding or surgery ≤2 weeks ago, stroke ≤1 month ago, bleeding disorder or platelet count <75 × 10⁹/L, uncontrolled HTN (sBP >180 or dBP >110), or by clinician judgment

>24 hrs on supplemental oxygen required to maintain SaO₂ >90%

PE diagnosed while on anticoagulation

Severe pain needing IV pain medication required >24 hr

Medical or social reason for admission >24 hr (infection, malignancy, no support system)

Creatinine clearance <30 mL/min by Cockcroft-Gault formula

Severe liver impairment

By clinician judgment

Pregnant

Documented history of Heparin-Induced Thrombocytopenias