Papillary thyroid cancer

• Most common form (85% of differentiated thyroid cancers); peak incidence 30 to 50 y
• Risk factors: childhood radiation exposure, FHx in 1° relative, familial syndrome
• Low-risk, mort. 1–2% at 20 y; mets to neck LN common, but prognosis remains good
• Rx is surgery; after surgical resection, RAI in select intermediate-risk or high-risk