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General management principles-of-metastatic breast cancer

  • Goal of tx:
    • ↑ survival, ↓ sxs, ↑ QoL
    • Systemic therapy
      • prioritizing nonchemo options 1st, per ER/HER2
    • local intervention (eg, surgery/RT)
      • for symptomatic control & imminent organ threat
      • eg, bone pain, cord compression, brain met

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