Clinical manifestations-hyperaldosteronism

• Mild-to-moderate HTN:
  • 16-22% of all HTN, 11% of refractory cases (Annals 2020;173:10)
• Headache,
• muscle weakness,
• polyuria,
• polydipsia;
• no peripheral edema because of “escape” from Na retention;
• malignant HTN is rare

Classically

• hypokalemia (but often normal),
• metabolic alkalosis,
• mild hypernatremia