non- nucleoside reverse transcriptase inhibitor-NNRTI-Antiretrovirals (ARVs)

efavirenz (EFV; Sustiva) etravirine (ETR; Intelence) nevirapine (NVP; Viramune) rilpivirine (RPV; Edurant) Class: rash, hepatitis, mixed CYP450 inducer/inhib EFV: CNS effects (incl depression) NVP: rash and hypersensitivity [risk factors are female, CD4 >250, pregnancy (∴ avoid)]