Definition-necrotizing soft-tissue infections

• Fulminant tissue destruction, systemic toxicity & high mortality. Surgical emergency.
• May include cellulitis, fasciitis, myositis, myonecrosis (gas gangrene).

Risk factors

• Can affect healthy individuals via skin/mucosal breach or traumatic wound,
• but ↑ risk w/ DM, PVD, EtOH abuse, IVDU, cirrhosis, or other immunosupp.
  • diabetes mellitus, peripheral vascular disease, 喝酒, 肝硬化，或免疫不好的病人