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🌱 來自: peripheral artery disease

Treatment-peripheral artery disease

(JACC 2013;61:1555, Circ 2021;144:e171, JAMA 2021;325:2188)

• Risk factor modif.
• Screen for CAD/AAA. Structured high-intensity walking
  • (JAMA 2021;325:1266).
• If sx or if asx with ABI ≤0.90,
  • ASA, clopi, or ticag to ↓ D/MI/stroke (NEJM 2017; 376:32).
  • More intensive antiplt Rx ↓ both MACE & limb ischemic events (JACC 2016;67:2719).
  • Adding riva 2.5 mg bid to ASA ↓ MACE but ↑ bleeding
    • (Lancet 2018;391:219; NEJM 2020;382:1994).
• Statins & PCSK9i ↓ MACE & limb ischemic events
  • (Circ 2018;137:338). Cilostazol (if no HF).
• Endovascular (angioplasty vs. stent) or surgical revasc if limiting/refractory sx or CLI