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🌱 來自: Huppert’s Notes
Antifungal Therapies🚧 施工中
Antifungal Therapies
First-line treatments for invasive fungal infections
• Anti-fungal agents: See Table 8.24 for antifungal therapies and spectrums of their coverage
• Invasive candidiasis (e.g., candidemia): Initiate echinocandins are 1st line for invasive candidiasis
- Can transition to fluconazole for some species (e.g., C. albicans)
- C. krusei is intrinsically resistant to fluconazole
- If Candida spp. cultured from bloodstream, consult ID and also consult ophthalmology to evaluate for endophthalmitis
• Concern for angioinvasive fungal infection:
- Suspect mucormycosis: Initiate empiric amphotericin B
- Suspect invasive Aspergillus: Initiate empiric voriconazole
TABLE 8.24 • Spectrum of Coverage for Antifungal Agents