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🌱 來自: Huppert’s Notes

Post-Intensive Care Syndrome & Other Long-Term Physical and Cognitive Disability🚧 施工中

Post-Intensive Care Syndrome & Other Long-Term Physical and Cognitive Disability

•   Definition: Generally defined as new or worsening cognitive, psychiatric, and/or physical function

-   Cognitive: Memory, executive function

-   Psychiatric: Depression, anxiety, PTSD

-   Physical: ICU-acquired weakness is most common

•   Risk factors:

-   Pre-existing factors: Neuromuscular disorders, prior cognitive impairment, psychiatric disease, frailty, medical comorbidities

-   ICU-specific factors: Mechanical ventilation, delirium, sepsis, ARDS

•   Management:

-   Daily sedation interruptions, delirium avoidance and management, early ambulation and physical therapy, nutritional optimization, avoidance of hypoglycemia and hypoxemia

-   Post-discharge treatment with physical therapy and rehab, occupational therapy, social support, mental health services

•   Clinical importance:

-   Survivors of critical illness report lower quality of life (QOL) scores

-   Family members of survivors report lower QOL scores

-   Survivors of critical illness have higher likelihood of rehospitalization, higher unemployment rates, and higher overall mortality