Continuous veno-venous hemofiltration (CVVH)
- Hemofiltration rather than dialysis.
- Blood under pressure passes down one side highly permeable membrane filtering H2O and solutes via TMP gradient (convective clearance); filtrate discarded.
- Replacement fluid infused (solute concentration similar to plasma, except no urea, Cr, PO4).
- Fluid balance by adjusting filtrate/replacement fluid.
Replacement fluid of continuous veno-venous hemofiltration
Other CRRT modalities:
CVVHD (dialysis), CVVHDF (filtration & dialysis) (AJKD 2016;68:645)
Benefits compared w/ HD:
↓ gross fluid shift (preferred in HoTN), but slower clearance of solutes and toxins