mitral-valve-prolapse
Definition and Etiology
- Billowing of MV leaflet ≥2 mm above mitral annulus in parasternal long axis echo view
- Primary: sporadic or familial myxomatous proliferation of spongiosa of MV apparatus
- Secondary: trauma, endocarditis, congenital, CTD (eg, Marfan’s, OI, Ehlers-Danlos) Clinical manifestations (usually asymptomatic)
- MR, endocarditis, emboli, arrhythmias (rarely SCD from VT from papillary muscle)
- High-pitched, midsystolic click (earlier w/ ↓ preload) ± mid-to-late systolic murmur
- No Rx per se [endocarditis Ppx not rec. (Circ 2007;116:1736)]; Rx MR as above