Info

🌱 來自: Epidemiology and risk factors-of-NSCLC

cigarette smoking

• 85% of all cases (20× relative risk over nonsmokers),
• ↑ w/ intensity & dur of smoking,
• ↓ w/ time since quitting;

other risks

• Second-hand smoking,
• previous RT,
• air pollution,
• radon,
• metals,
• asbestos,
• synergy w/ smoking + asbestos,
• germline TP53 & EGFR T790M comprise a small fraction (Mayo Clin Proc 2008;83:584)