Peritoneal dialysis (PD)
(JAMA 2017;317:1864)
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Fluid removed via convection using oncotic pressure (eg, dextrose). ↑ concentrations and dwell times removes more fluid (less as glc equilibrates).
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PD fluid: dextrose (1.5%, 2.5%, or 4.25%), buffer (lactate), Na+, Ca2+, Mg2+
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Infuse 10 min, dwell 90 min–5.5 h, drain 20 min; exchanges done manually or using cycler at night (automated or cont. ambulatory peritoneal dialysis APD, CAPD)
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Hyperglycemia: exacerbated by inflammation, long dwell times, and higher [glucose]
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Benefits: lower cost, independence, preservation of residual kidney function. No Δ mortality vs. HD (AJKD 2018;71:344).