Info

Diagnosis of hepatocellular carcinoma

  • Can diagnose w/o biopsy in high-risk Pts with 3-phase contrast CT or MRI
  • Only 15% of liver masses are HCC; liver metastases from other 1° more common

Figure: Natural history, impact of therapies, and unmet needs in hepatocellular carcinoma (HCC). AFP, α fetoprotein; ECOG, Eastern Cooperative Oncology Group performance status; mAb, monoclonal antibody; TACE, transarterial chemoembolization; TKI, tyrosine kinase inhibitor.


StageEcoGChild-Pugh
00A
A-C0A/B
D3-4C

Stage 0

Stage A-C

StageCriteriaECOG
Early stage (A)1 HCC or 3 nodules ≤ 3 cmECOG 0
Intermediate stage (B)MultinodularECOG 0
Advanced stage (C)Portal invasion, N1, M1ECOG 1/2

Stage D: End stage