Info

🌱 來自: gout

Etiologies of gout

  • UrA underexcretion (85-90%):
    • meds (eg, diuretics);
    • idiopathic;
    • ↓ renal function;
    • obesity
  • Uric acid (UrA) overproduction (10-15%): ↑
    • meat,
    • seafood,
    • EtOH,
    • psoriasis,
    • idiopathic,
    • myelo- and lymphoproliferative disease,
    • chronic hemolytic anemia,
    • cytotoxic drugs,
    • rare inherited enzyme defic,
    • genetic variants (Nature Rev Rheumatol 2018;14:341)