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🌱 來自: Indirect hyperbilirubinemia

Crigler-Najjar syndrome

• Clinical manifestations and classification

  • Crigler-Najjar syndrome, also referred to as congenital nonhemolytic jaundice with glucuronosyltransferase deficiency,
  • is → a rare autosomal recessive disorder of bilirubin metabolism.
  • It has been divided into two forms (types I and II) based on the hepatic bilirubin-UGT1A1 activity,
  • which correlates with disease severity and risk for neurologic sequelae

• Crigler-Najjar syndrome type I

• Crigler-Najjar syndrome type II