Info

🌱 來自：connective tissue diseases

systemic sclerosis and scleroderma disorders

• CREST Syndrome
  • “C” : 鈣 : calcinosis, where calcium deposits form under the skin on the fingers or other areas of the body.
  • “R” : 雷：Raynaud’s phenomenon, spasm of blood vessels in the fingers or toes in response to cold or stress.
  • “E” : 食道 : esophageal dysmotility, which can cause difficulty in swallowing.
  • “S” : 大手指 : sclerodactyly, tightening of the skin causing the fingers to bend.
  • “T” : 血管擴張 : telangiectasia, dilated vessels on the skin of the fingers, face, or inside of the mouth.
• Usually only 2 of the 5 symptoms of the CREST syndrome is → necessary to be diagnosed with the disease.

---

• Definition and epidemiology 󰒖 (Best Pract Res Clin Rheumatol 2018;32:223)
• ACR-EULAR SSc classification criteria (Ann Rheum Dis 2013;72:1747)
• clinical manifestations of systemic sclerosis
• SSc Subgroup Comparison
• Diagnostic studies and monitoring 󰒖
• Treatment 󰒖